虹膜角膜内皮综合征是近年来才被认识的一种少见病,它包括原发性进行性虹膜萎缩、Chandler氏综合征和虹膜痣综合征(CoganRcesc Syndrome),三者在临床症状方面有着共同的特征:①虹膜周边前粘连,②角膜内皮异常及水肿,③虹膜萎缩、瞳孔变形及移位,④单眼继发性青光眼。三者在组织病理方面也有许多共同之处,而症状又互相交错,且有变种和中间型,因此,新近文献已将此类疾病通称为虹膜角膜内皮综合征(ICE综合征)。现将主要文献资料综述如下: Iris Corneal endothelium syndrome is a rare disease that has been recognized in recent years and includes idiopathic progressive iris atrophy, Chandler’s syndrome and Cogan’s syndrome, all of which have common clinical symptoms Features: ① iris before the adhesion, ② corneal endothelial abnormalities and edema, ③ iris shrinkage, pupil deformation and displacement, ④ monocular secondary glaucoma. The three have many similarities in histopathology, and the symptoms are staggered with variations and intermediates. Therefore, recent literature has referred to these diseases as iris corneal endothelial syndrome (ICE syndrome). The main literature is summarized as follows: