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目的:回顾性分析影响胃癌淋巴结转移的诸因素,为合理制定根治术式提供理论依据.方法:分析554例胃癌切除术患者的病史、手术记录和病理检测结果资料.应用BMDP软件包计算不同部位淋巴结转移者术后逐年生存率,采用单因素和Logistic回归多因素分析方法探讨胃癌临床病理特点与淋巴结转移的关系.结果:淋巴结转移者和无转移者5年生存率分别为31.04%和90.9%.单因素分析发现,大体类型、分化程度、浸润深度、原发部位及肿瘤大小均与淋巴结转移有关;多因素分析则发现肿瘤浸润深度及肿瘤大小为影响淋巴结转移的独立因素.结论:淋巴结转移是影响胃癌患者预后的重要因素,而胃癌的临床病理特点与淋巴结转移密切相关.
Objective: To retrospectively analyze various factors affecting lymph node metastasis of gastric cancer and provide a theoretical basis for the rational development of radical surgery. Methods: Analyze the history, surgical records, and pathological findings of 554 patients with gastric cancer resection. Calculate different sites using BMDP software package The survival rate of lymph node metastasis was determined by single factor analysis and Logistic regression multivariate analysis. The results showed that the 5-year survival rates of lymph node metastasis and non-metastasis were 31.04% and 90.9%, respectively. Univariate analysis found that gross type, differentiation degree, depth of invasion, primary site, and tumor size were all related to lymph node metastasis. Multivariate analysis found that tumor invasion depth and tumor size were independent factors affecting lymph node metastasis. Conclusion: Lymph node metastasis Is an important factor affecting the prognosis of gastric cancer patients, and the clinicopathological features of gastric cancer are closely related to lymph node metastasis.