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目的分析川崎病并发冠状动脉病变(CAL)的影响因素。方法选取川崎病患儿114例,根据是否合并CAL,分为合并CAL 21例(CAL组),无CAL 93例(NCAL组)。回顾性分析两组患儿临床资料。结果 CAL组患儿热程>10d比例高于NCAL组(71.4%vs.37.6%)(P<0.05),CAL组患儿红细胞沉降率(ESR)、血小板(Plt)、C-反应蛋白(CRP)、心肌肌钙蛋白(cTnI)高于NCAL组(P<0.05),血清白蛋白(Alb)低于NCAL组(P<0.05)。结论热程>10d、Alb下降、cTnI升高是川崎病发生CAL的高危因素。
Objective To analyze the influencing factors of Kawasaki disease complicated with coronary artery disease (CAL). Methods One hundred and fourteen children with Kawasaki disease were enrolled and divided into CAL group (CAL group) and no CAL group (NCAL group). The clinical data of two groups of children were retrospectively analyzed. Results The calorific value of children in CAL group was higher than that of NCAL group (71.4% vs.37.6%, P <0.05). The erythrocyte sedimentation rate (ESR), platelet (Plt), C-reactive protein ), Cardiac troponin (cTnI) was higher than NCAL group (P <0.05), serum albumin (Alb) was lower than NCAL group (P <0.05). Conclusions Heat loss> 10 days, Alb decreased, elevated cTnI Kawasaki disease risk factors for CAL.