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作者对非洲冈比亚河北岸5个村庄1~4岁儿童在接种脑膜炎球菌荚膜多糖菌苗后的抗体水平作了长期测定,并对加强免疫的作用和抗疟预防药物对接种的影响进行了研究。1983年11~12月对>1岁儿童接种1剂25μgA群+C群脑膜炎球菌荚膜多糖菌苗,取免疫前及免疫3周、两年和5年后的血清
The authors conducted a long-term measurement of antibody levels in children aged 1 to 4 years in five villages on the northern bank of the Gambia River in Africa after inoculation of the meningococcal capsular polysaccharide vaccine and evaluated the effect of boosting immunity and the effect of antimalarial prophylaxis on vaccination the study. From January to December 1983, one-year-old children were inoculated with one dose of 25μgA + C meningococcal capsular polysaccharide vaccine, and serum taken before immunization and three weeks, two years and five years after immunization