患者,男性,27岁。自幼有肝脾肿大,9岁生长发育迟缓,15岁后生长停止。10岁因血小板减少时有鼻衄,牙龈出血,皮肤淤斑。1982年右(足母)趾关节出现红肿灼痛,逐渐累及左(足母)趾、膝、踩、肘关节,伴活动受限,疼痛夜间加剧,清晨缓解,反复发作。1986年两(足母)趾关节伸面出现黄白色结节,逐渐增大至杨梅大小,偶有痛感。结节 Patient, male, 27 years old. Since childhood, hepatosplenomegaly, 9-year-old growth retardation, growth stopped after the age of 15. 10 years old due to thrombocytopenia epistaxis, bleeding gums, skin ecchymosis. In 1982 the right (foot mother) toe joint swelling pain, gradually involving the left (foot mother) toes, knees, tread, elbow joint, with limited activity, increased pain at night, early morning relief, recurrent. In 1986, two (foot mother) toe joint extension yellowish white nodules, and gradually increased to the size of bayberry, occasionally pain. Nodules