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目的分析70例重症哮喘患者控制情况并寻求难以控制原因,评估哮喘患者生活质量。方法对70例重症哮喘患者进行为期一年的6次随访后,根据哮喘控制情况分组,并进行多因素与哮喘控制的相关分析,用哮喘生活质量问卷(AQLQ)和哮喘控制问卷(ACQ)评估生活质量。结果60例患者完成随访,达到控制16例,未达控制44例。哮喘急性加重总次数明显减少(P<0.001),鼻炎和哮喘控制显著相关(P<0.05),ACQ和AQLQ对生活质量起较好的评估作用,达到哮喘控制的患者有更好的支气管可逆性。结论重症哮喘的控制较为困难,早期干预和加强管理可以减轻严重程度,可通过改善患者鼻部症状而达到更好的哮喘控制。ACQ和AQLQ可进一步应用于临床来评估患者的生活质量。
Objective To analyze the control of 70 patients with severe asthma and find it difficult to control the cause and evaluate the quality of life of patients with asthma. Methods Sixty-one follow-up visits were performed in 70 patients with severe asthma. The patients were divided into groups according to the control of asthma. The correlation between multiple factors and asthma control was analyzed. AQLQ and ACQ were used to evaluate the effect of asthma control. Quality of Life. Results 60 patients completed follow-up, reaching control in 16 cases, up to control 44 cases. The total number of asthma exacerbations was significantly reduced (P <0.001), rhinitis was significantly associated with asthma control (P <0.05), ACQ and AQLQ were better assessed for quality of life, and patients with asthma control had better bronchial reversibility . Conclusions The control of severe asthma is more difficult. Early intervention and intensive management can reduce the severity and achieve better asthma control by improving nasal symptoms. ACQ and AQLQ can be further used clinically to assess the patient’s quality of life.