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目的探讨小剂量多巴酚丁胺负荷超声(LDDSE)评价急性心肌梗死(AMl)后存活心肌的价值及安全性。方法选择25例行急诊经皮冠状动脉介入治疗(PCI)AMI患者,PCI后14天进行LDDSE试验,以PCI术后3个月超声心动图检查室壁运动改善为评价存活心肌的金标准,观察LDDSE评价存活心肌的准确度,同时观察AMI早期行LDDSE的安全性。结果 LDDSE检测存活心肌的敏感度为82.5%,特异度78.5%,准确度为80.9%。在LDDSE过程中未见严重不良反应。结论 LDDSE可用于AMI患者存活心肌的评估,是一种较为安全、简便的评价存活心肌的方法。
Objective To evaluate the value and safety of low-dose dobutamine stress ultrasound (LDDSE) in assessing myocardial viability after acute myocardial infarction (AMI). Methods Twenty-five patients undergoing percutaneous coronary intervention (PCI) were enrolled in this study. LDDSE was performed 14 days after PCI. The improvement of ventricular wall motion was assessed by echocardiography 3 months after PCI as the gold standard for evaluating viable myocardium. LDDSE evaluated the accuracy of viable myocardium and observed the safety of LDDSE during early AMI. Results The sensitivity and specificity of LDDSE in detecting viable myocardium were 82.5%, 78.5% and 80.9% respectively. No serious adverse reactions were observed during LDDSE. Conclusions LDDSE can be used for the assessment of viable myocardium in patients with AMI. It is a safe and simple method to evaluate the viable myocardium.