近来有报道腐植酸制剂具有体内抗肿瘤作用,但无一般抗瘤药物所常有的毒副反应。它们可能促进了机体的免疫监视机能。已知巨噬细胞是免疫过程的调节者,也是灭瘤的效应细胞。因此我们试验黄腐酸钠(系本室从北京斋堂的低钙镁风化煤中提取的纯净物质)对单核巨噬细胞系统功能的影响,并作了毒性试验。实验方法与结果 Recently, it has been reported that humic acid preparations have the anti-tumor effect in vivo, but no common side effects of anti-tumor drugs. They may promote the body’s immune surveillance function. Macrophages are known to be regulators of the immune process and are also tumor suppressor effector cells. Therefore, we tested the effect of sodium fulvate on the function of mononuclear macrophage system and purified the toxic substances from the low calcium-magnesium weathered coal extracted from Beijing Zhaitang. Experimental methods and results