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于１９９６年７月～１０月，对大骨节病区１３６例，非病区４６例，７～１２岁儿童，进行了右手Ｘ线检查，同时测定了骨碱性磷酸酶（ＢＡＬＰ），结果查出大骨节病４６．３２％，ＢＡＬＰ查出５６．６２％，ｘ线诊断与ＢＡＬＰ诊断符合率为９２．０６％。在大骨节病区Ｘ线检查正常者中，ＢＡＬＰ检出阳性率为２６．０３％，结果证明，ＢＡＬＰ测定方法，对儿童大骨节病筛查及诊断有较高的临床应用价值。
From July to October 1996, 136 patients with KBD, 46 patients with non-PA, and 7-12-year-old children underwent right-handed X-ray examination. Bone alkaline phosphatase (BALP) was measured at the same time. Results Bone disease was 46.32%, BALP was 56.62%, the coincidence rate of X-ray diagnosis and BALP was 92.06%. The positive rate of BALP was 26.03% in patients with normal X-ray examination in Kashin-Beck disease area. The results showed that the BALP determination method had a high clinical value in the screening and diagnosis of Kashin-Beck disease in children.