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已经发现梅尼埃病人的体内有循环免疫复合物的存在即直接针对n型胶原的特异性抗体,而B型胶原是哺乳类动物内耳的成分之一,通过给豚鼠体内重复注射三型胶原时梅尼埃病可重复出现。这些事实证明梅尼埃病符合Witebsky设定的自身免疫性疾病分类中大部分条件。病人血清中非器官性
It has been found that the presence of circulating immunocomplexes in Meniere’s patients, ie specific antibodies directed against n-type collagen, is one of the components of the inner ear of mammals. Repeated injections of type I collagen into guinea pigs Meniere’s disease can recur. These facts prove that Meniere’s disease meets most of the conditions set by Witebsky in the classification of autoimmune diseases. Patient serum non-organ