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目前在国内将脂质体用于疫苗的领域尚未见报道。我们摸索了不同的脂质体合成技术,制备合适的脂质体包被甲肝减毒活疫苗,重组乙肝疫苗、白喉类毒素和破伤风类毒素,开发脂质体疫苗的合成途径,以根据不同疫苗的特点和免疫途径生产相应的脂质体疫苗。1材料与方法1.1材料磷脂酸
Currently in the field of liposomes for the vaccine has not been reported in the area. We explored different liposome synthesis techniques to prepare appropriate liposomes coated live attenuated hepatitis A vaccine, recombinant hepatitis B vaccine, diphtheria toxoid and tetanus toxoid, the development of liposomal vaccine synthesis pathway, according to different The characteristics of the vaccine and the immunization route produce the corresponding liposomal vaccine. 1 Materials and Methods 1.1 Materials Phosphatidic acid