Thermochronological datasets for the Kyrgyz Tianshan and Siberian Altai-Sayan within Central Asia reveal a punctuated exhumation history during the Meso-Cenozoic.In this paper,the datasets for both regions are collectively reviewed in order to speculate on the links between the Meso-Cenozoic exhumation of the continental Eurasian interior and the prevailing tectonic processes at the plate margins.Whereas most of the thermochronological data across both regions document late Jurassic-Cretaceous regional basement cooling,older landscape relics and dissecting fault zones throughout both regions preserve Triassic and Cenozoic events of rapid cooling,respectively.Triassic cooling is thought to reflect the Qjangtang- Eurasia collision and/or rifting/subsidence in the West Siberian basin.Alternatively,this cooling signal could be related with the terminal terrane-amalgamation of the Central Asian Orogenic Belt.For the Kygyz Tianshan,late Jurassic-Cretaceous regional exhumation and Cenozoic fault reactivations can be linked with specific tectonic events during the closure of the Palaeo-Tethys and Neo-Tethys Oceans,respectively.The effect of the progressive consumption of these oceans and the associated collisions of Cimmeria and India with Eurasia probably only had a minor effect on the exhumation of the Siberian Altai-Sayan.More likely,tectonic forces from the east(present-day coordinates) as a result of the building and collapse of the Mongol-Okhotsk orogen and rifting in the Baikal region shaped the current Siberian Altai-Sayan topography.Although many of these hypothesised links need to be tested further,they allow a first-order insight into the dynamic response and the stress propagation pathways from the Eurasian margin into the continental interior. Thermochronological datasets for the Kyrgyz Tianshan and Siberian Altai-Sayan within Central Asia reveal a punctuated exhumation history during the Meso-Cenozoic. In this paper, the datasets for both regions are collectively reviewed in order to speculate on the links between the Meso-Cenozoic exhumation of the continental Eurasian interior and the prevailing tectonic processes at the plate margins .Whereas most of the thermochronological data across both regions document late Jurassic-Cretaceous regional basement cooling, older landscape relics and dissecting fault zones throughout both regions preserve Triassic and Cenozoic events of rapid cooling, respectively.Triassic cooling is thought to reflect the Qjangtang- Eurasia collision and / or rifting / subsidence in the West Siberian basin. Alternatively, this cooling signal could be related with the terminal terrane-amalgamation of the Central Asian Orogenic Belt. For the Kygyz Tianshan, late Jurassic-Cretaceous regional exhumation and Cenozoic fa ult reactivations can be linked with specific tectonic events during the closure of the Palaeo-Tethys and Neo-Tethys Oceans, respectively. The effect of the progressive consumption of these oceans and the associated collisions of Cimmeria and India with Eurasia probably only had a minor effect on the exhumation of the Siberian Altai-Sayan. More likely, tectonic forces from the east (present-day coordinates) as a result of the building and collapse of the Mongol-Okhotsk orogen and rifting in the Baikal region shaped the current Siberian Altai- Sayan topography .Although many of these hypothesised links need to be tested further, they allow a first-order insight into the dynamic response and the stress propagation pathsways from the Eurasian margin into the continental interior.