端粒酶是催化合成并维持端粒一定序列的一种核糖核蛋白，是一种专一的逆转录酶。目前端粒酶的检测方法包括：（１）基本方法；（２）ＴＲＡＰ法；（３）ＥＬＩＳＡ法；（４）接近闪烁分析法；（５）原位杂交法。大多数肿瘤细胞都有端粒酶活性表达，端粒酶与肿瘤细胞存在高度相关性，端粒酶检测方法的不断发展为肿瘤的诊断和治疗提供了新途径 Telomerase is a ribonucleoprotein that catalyzes the synthesis and maintenance of a certain sequence of telomeres and is a specific reverse transcriptase. At present, telomerase detection methods include: (1) basic methods; (2) TRAP method; (3) ELISA method; (4) near scintillation analysis method; (5) in situ hybridization method. Telomerase activity is expressed in most tumor cells, and telomerase is highly correlated with tumor cells. The continuous development of telomerase detection methods provides a new approach for the diagnosis and treatment of tumors.