目的:评价经皮穴位电刺激对胸腔镜手术患者苏醒期躁动的影响。方法:择期全身麻醉下行胸腔镜手术患者80例，性别不限，年龄25~64岁，BMI 18~30 kg/mn 2，ASA分级Ⅱ或Ⅲ级，采用随机数字表法分为2组(n n＝40)：经皮穴位电刺激组(T组)和对照组(C组)。T组于麻醉诱导前30 min开始至术毕刺激合谷、足三里和三阴交穴，频率2/100 Hz，疏密波，刺激强度以患者所能耐受的最大电流为宜；C组在合谷、足三里及三阴交穴贴电极片，但不给予穴位电刺激。记录患者苏醒期Ramsay镇静评分和VAS评分，采用RSS躁动评分评价躁动发生情况；于麻醉诱导前(Tn 1)、术毕(Tn 2)、拔除气管导管即刻(Tn 3)和拔除气管导管后15 min(Tn 4)时采集肘正中静脉或颈内静脉血样，采用ELISA法测定血清IL-6和IL-10浓度；记录术中丙泊酚、瑞芬太尼和舒芬太尼用量；记录术后心动过速、心动过缓、高血压、低血压、呼吸抑制、苏醒延迟、恶心呕吐等不良反应的发生情况。n 结果:与C组比较，T组术中瑞芬太尼用量减少，Tn 2~4时血清IL-6浓度降低，血清IL-10浓度升高，Ramsay镇静评分增加，躁动发生率降低(n P0.05)。n 结论:经皮穴位电刺激可降低胸腔镜手术患者苏醒期躁动的发生，与抑制炎症反应有关。“,”Objective:To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) on emergence agitation in the patients undergoing thoracoscopic surgery.Methods:Eighty patients of both sexes, aged 25-64 yr, with body mass index of 18-30 kg/mn 2, of American Society of Anesthesiologists physical status Ⅱ or Ⅲ, undergoing elective thoracoscopic surgery under general anesthesia, were divided into 2 groups (n n=40 each) by a random number table method: TEAS group (group T) and control group (group C). In group T, the Hegu (L14), Zusanli (ST36) and Sanyinjiao (SP6) were stimulated starting from 30 min before induction of anesthesia until the end of operation, with a frequency of 2/100 Hz and disperse-dense waves.The intensity of stimulation was the maximum current that patients could tolerate.In group C, stimulating electrodes were placed at the same acupoints before induction, but no electrical stimulation was applied.Ramsay sedation score and VAS score were recorded.and emergence agitation was assessed using RSS agitation score.Blood samples from the median cubital vein or internal jugular vein were collected before anesthesia induction (Tn 1), at the end of surgery (Tn 2), immediately after removal of tracheal tube (Tn 3) and at 15 min after removal of tracheal tube (Tn 4) for determination of serum interleukin-6 (IL-6) and IL-10 concentrations by enzyme-linked immunosorbent assay.The intraoperative consumption of propofol, remifentanil and sufentanil was recorded.Adverse reactions such as tachycardia, bradycardia, hypertension, hypotension, respiratory depression, delay of awakening and nausea and vomiting were recorded after operation.n Results:Compared with group C, the amount of intraoperative remifentanil consumed was significantly decreased, serum IL-6 concentrations were decreased, and the serum IL-10 concentration was increased Tn 2-4, Ramsay sedate score was increased, and the incidence of agitation was decreased in group T (n P0.05).n Conclusions:TEAS can reduce the development of emergence agitation in the patients undergoing thoracoscopic surgery, which is related to inhibition of inflammatory responses.