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目的观察左氧氟沙星应用于妇产科感染患者中的治疗效果。方法选取医院接诊治疗的妇产科感染患者38例,患者口服左氧氟沙星片(商品名:可乐必妥片)治疗,每次300 mg,每天2次,用药时间为7~14 d。用药期间严密观察患者的体温、腹痛、下腹部压痛、附件压痛、子宫举痛等症状改善情况;治疗前后分别观察白带、宫颈分泌物颜色,治疗前后进行白带细菌培养了解患者感染菌株情况,同时进行血常规、肝肾功能等检查了解患者病情变化;用药期间详细记录不良反应发生情况,统计不良反应发生率。结果 38例患者痊愈33例,痊愈率为86.8%,总有效率为94.7%(36/38)。细菌清除34例,细菌清除率为89.5%。治疗期间3例患者出现恶心、纳差、胃部不适等不良发应,未发现肝肾功能损害等严重不良反应。结论妇产科感染患者应用左氧氟沙星治疗效果明显,具有较高的应用价值,值得临床推广应用。
Objective To observe the therapeutic effect of levofloxacin in obstetrics and gynecology patients. Methods Thirty-eight patients with obstetrics and gynecology infection admitted to hospital were enrolled in this study. Patients were treated with levofloxacin tablets (trade name: Colabitone) 300 mg twice daily for 7-14 days. During the treatment of patients closely observe the body temperature, abdominal pain, lower abdominal tenderness, attachment tenderness, uterine pain and other symptoms improved; before and after treatment were observed leucorrhea, cervical secretion color, before and after treatment of leucorrhea bacterial infection in patients infected with the situation, at the same time Blood, liver and kidney function tests to understand the patient’s condition changes; medication recorded in detail the occurrence of adverse reactions, statistics, the incidence of adverse reactions. Results 38 patients were cured in 33 cases, the cure rate was 86.8%, the total effective rate was 94.7% (36/38). 34 cases of bacterial clearance, bacterial clearance rate of 89.5%. During the treatment, 3 patients had nausea, anorexia, stomach discomfort and other adverse reactions, and no serious adverse reactions such as liver and kidney dysfunction were found. Conclusion Obstetrics and gynecology patients with levofloxacin treatment effect is obvious, has a high value, it is worth clinical application.