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患者女性,26岁.3岁起患慢性肾盂肾炎,当时即患有鱼鳞病,并因肾功能逐渐恶化而加重.患者鱼鳞病为全身性,特别是膝、肘和上臂伸侧,日光照射可使改善,无鱼鳞病家族史.一年前作肾移植术,术后9天肾功能明显改善,鱼鳞病也自移植时开始改善,并在以后完全消退.移植开始时用环孢菌素,所用其他药物还有强的松龙、美多心安和胍唑嗪.肾移植6月后,用硫唑嘌呤代替环孢菌素,而鱼鳞病至今未复发.
Female, 26 years old Chronic pyelonephritis at 3 years of age with ichthyosis at that time and exacerbated by worsening renal function Patients with ichthyosis are generalized, particularly in the knee, elbow and upper arm extensors, and sunlit To improve, no family history of ichthyosis. A year ago for kidney transplantation, renal function improved significantly after 9 days, ichthyosis began to improve from the time of transplantation, and completely subsided after the beginning of transplantation with cyclosporin, the use of Other medications include prednisolone, metoprolol and benzadiazine, and azathioprine replaced cyclosporine after 6 months of kidney transplantation, but ichthyosis has not relapsed so far.