【摘 要】
：
An efficient synthetic protocol for the 1,4-diaryl-1,4-dihydropyridines was developed via the domino four-component reaction of arylamine,acetylenedicarboxylate
【出 处】
：
Chemical Research in Chinese Universities
论文部分内容阅读
An efficient synthetic protocol for the 1,4-diaryl-1,4-dihydropyridines was developed via the domino four-component reaction of arylamine,acetylenedicarboxylate,aromatic aldehyde and ethyl acetoacetate.The reaction mechanism involves the formation of β-enamino ester and its sequential Michael addition to arylidene acetoacetate.
An efficient synthetic protocol for the 1,4-diaryl-1,4-dihydropyridines was developed via the domino four-component reaction of arylamine, acetylenedicarboxylate, aromatic aldehyde and ethyl acetoacetate. The reaction mechanism involves the formation of β-enamino ester and its sequential Michael addition to arylidene acetoacetate.
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