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目的 研究 8-MOP与ATRA联合应用对Mc3细胞膜表面凝集素受体表达的影响。方法 免疫组织化学染色方法。结果 对照组凝集素受体表达分别为 :PNA(+～ + + ) ,UEA(-～ + + ) ,SBA(+～ + + ) ,RCA(+～ + + ) ;8-MOP组凝集素受体表达分别为 :PNA(-～ + + ) ,UEA(+ ) ,SBA(+ ) ,RCA(+～ + + ) ;ATRA组凝集素受体表达分别为 :PNA(-～ + + ) ,UEA(+ ) ,SBA(+～ + + ) ,RCA(+ ) ;8-MOP +ATRA组凝集素受体表达分别为 :PNA(-～ + + ) ,UEA(+ ) ,SBA(-～ + ) ,RCA(+～ + + )。结论 PNA ,UEA ,SBA和RCA染色强度的下降或增高可能提示肿瘤倾向于良性分化
Objective To investigate the effect of 8-MOP combined with ATRA on the expression of lectin receptor on membrane surface of Mc3 cells. Methods Immunohistochemical staining methods. Results The expression of lectin receptor in control group were: PNA (+ ~ + +), UEA (+ ~ + +), SBA (+ ~ + +), RCA The expression of lectin receptors in ATRA group were PNA (- ~ + +), UEA (+), SBA (+) and RCA (+), SBA (+ ~ + +) and RCA (+); The expression of lectin receptors in 8-MOP + ATRA group were: PNA , RCA (+ ~ + +). Conclusion The decrease or increase of the staining intensity of PNA, UEA, SBA and RCA may indicate that the tumors tend to benignly differentiate