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为探讨毛细支气管炎(简称毛支)与支气管哮喘(简称BA)在发病机理上相关性及毛支的诊治原则。测定了毛支患儿血清IgE及循环免疫复合物(CIC)中各组分含量,同时作BA运动激发试验、蒸馏水激发试验、组织胺激发试验及色甘酸钠(SCG)保护试验。结果提示反复发作型毛支的IgE升高,毛支的CIC各组分含量均高于正常儿。毛支随访儿的运动激发试验阳性率为46.93％,BA缓解期的蒸馏水激发试验阳性率达92.98％,组织胺激发试验阳性率为96.49％,SCG保护指数是89.95=10.87％;认为小儿毛细支气管炎中的反复发作型,是将来发展成BA的潜在型;同时对毛支的治疗原则提出建议。
To investigate the relationship between the pathogenesis of bronchiolitis (bronchiolitis) and bronchial asthma (abbreviated as BA) and the diagnosis and treatment of bronchiolitis. The contents of serum IgE and circulating immune complex (CIC) in the children with bronchiolitis were measured. BA exercise challenge test, distilled water challenge test, histamine challenge test and cromolyn sodium (SCG) test were also carried out. The results suggest that repeated episodes of hair branch of the IgE increased, CIC branch hair content were higher than normal children. The positive rate of motility test was 46.93%. The positive rate of distilled water challenge test in BA remission period was 92.98%. The positive rate of histamine challenge test was 96.49%, and the SCG protection index was 89.95%. 10.87% Repeated episodes of inflammation in the future is the potential type of development into BA; the same time, the principle of treatment of hair branch make recommendations.