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本文应用放免法测定了68例充血性心衰病人血清β_2-m浓度。结果显示:心衰组β_2-m值明高于正常参照组(P<0.01),并随着心力衰竭程度的加重,β_2-m值逐渐增高;β_2-m检测肾小球滤过功能障碍的阳性率(75％)高于BUN(41.5％)和Cr(13.3％)。提出血清β_2-m检测可作为心衰病人的常规检查项目,对及早发现心衰并发的肾脏损害具有实用价值。
In this paper, 68 patients with congestive heart failure serum β 2-m concentration was measured by radioimmunoassay. The results showed that the β_2-m value of heart failure group was significantly higher than that of the normal reference group (P <0.01), and with the increase of heart failure, the β_2-m value gradually increased; β_2-m detection of glomerular filtration dysfunction The positive rate (75%) was higher than BUN (41.5%) and Cr (13.3%). It is suggested that serum β_2-m test can be used as a routine check-up for patients with heart failure and has practical value for early detection of renal damage complicated by heart failure.