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目的:探讨乳腺癌手术患者内科合并疾病与术后皮下积液发生的关系。方法:收集130例乳腺癌患者的相关临床资料,前瞻性观察其是否发生积液,单因素分析和多因素分析比较积液组与对照组在积液发生危险因素上的差异。结果:单因素分析显示积液组平均年龄大(59.13岁vs51.37岁,P=0.002),体质量指数(body mass index,BMI)大(25.33vs22.90,P=0.018),合并高血压者多(30.4%vs12.1%,P=0.027)。Logistic回归分析显示年龄(OR=1.065,95%CI=1.012～1.116,P=0.016)、BMI(OR=1.193,95%CI=1.025～1.389,P=0.023)是皮下积液发生的独立危险因素。结论:乳腺癌术后皮下积液的发生与年龄、BMI、合并内科疾病有关,注重围术期的调整处理可能有助于减少皮下积液的发生。
Objective: To investigate the relationship between medical complications and postoperative subcutaneous effusion in breast cancer patients. Methods: The clinical data of 130 patients with breast cancer were collected and prospectively observed for effusion, univariate analysis and multivariate analysis to compare the risk factors of effusion between effusion group and control group. Results: Univariate analysis showed that the mean age of the patients in the effusion group (59.13 vs 51.37 years, P = 0.002), body mass index (BMI) was larger (25.33 vs 22.90, P = 0.018) (30.4% vs 12.1%, P = 0.027). Logistic regression analysis showed that age (OR = 1.065,95% CI = 1.012-1.116, P = 0.016), BMI (OR = 1.193,95% CI = 1.025-1.389, P = 0.023) were independent risk factors for subcutaneous effusion . Conclusion: The occurrence of subcutaneous effusion after breast cancer is related to age, BMI and medical problems. Paying attention to perioperative adjustment may help to reduce the occurrence of subcutaneous effusion.