论文部分内容阅读
用酶抗酶免疫复合物（ＰＡＰ）法测定了５０例喉鳞状细胞癌及１０例声带息肉，１例声带乳头瘤样增生的雌激素受体（ＥＲ）和孕激素受体（ＰｇＲ）。结果表明，正常喉组织及声带息肉雌、孕激素受体均为阴性。喉鳞状细胞癌的雌、孕激素受体的阳性率分别为６０％和５６％，其中高分化鳞状细胞癌的雌、孕激素受体阳性率明显高于低分化者（Ｐ＜０．０５）。受体阳性率与临床分期无明显关系（Ｐ＞０．０５）。此结果提示雌激素受体的出现与喉癌细胞的分化程度有关。测定喉鳞状细胞癌的雌激素受体对于喉癌的发生、发展及预后有进一步研究的价值。
Fifty cases of laryngeal squamous cell carcinoma and 10 cases of vocal cord polyp and one case of papillary neoplasia with estrogen receptor (ER) and progesterone receptor (PgR) were detected by enzyme-linked immunosorbent assay (PAP). The results showed that the normal larynx and vocal cord polyps estrogen and progesterone receptors were negative. The positive rates of estrogen and progesterone receptors in laryngeal squamous cell carcinoma were 60% and 56%, respectively. The positive rates of estrogen and progesterone receptor in well-differentiated squamous cell carcinoma were significantly higher than those in poorly differentiated squamous cell carcinoma (P <0.05). 05). Receptor positive rate and clinical stage no significant relationship (P> 0.05). This result suggests that the occurrence of estrogen receptors and the degree of differentiation of laryngeal cancer cells. Determination of laryngeal squamous cell carcinoma estrogen receptor for the occurrence, development and prognosis of laryngeal cancer further study.