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目的分析尿激酶(UK)静脉溶栓治疗不稳定型心绞痛的效果及安全性。方法84例不稳定型心绞痛患者入院后随机分为两组:尿激酶静脉溶栓治疗组44例和常规治疗组40例,比较其治疗效果。结果尿激酶静脉溶栓组心电图ST段下降率达86·4%,胸痛缓解率达91%,常规治疗组ST段下降率为62·5%,胸痛缓解率65%,两组比较差异有统计学意义(P<0·01)。结论尿激酶溶栓治疗不稳定型心绞痛效果满意,不良反应少。
Objective To analyze the efficacy and safety of urokinase (UK) intravenous thrombolysis in the treatment of unstable angina pectoris. Methods Eighty-four patients with unstable angina pectoris were randomly divided into two groups: 44 patients received intravenous thrombolysis with urokinase and 40 patients received conventional therapy. The therapeutic effect was compared. Results In the Urokinase thrombolysis group, the rate of ST segment depression was 86.4% and the rate of chest pain was 91%. The ST segment decline rate was 62.5% and the rate of chest pain relief was 65% in the routine therapy group. There were statistically significant differences between the two groups Significance of learning (P <0.01). Conclusions Urokinase thrombolysis is effective in treating unstable angina pectoris with few adverse reactions.