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为了研究给儿童打一剂水痘疫苗的保护效果如何,探究怎样加强免疫。利用的方法是采集200份0到14岁的接种了一剂水痘疫苗的儿童的手指末梢血样,用定剂量的酶联免疫吸附试验来测定水痘IgG抗体,同时观察记录儿童的水痘患病率。试验结果表明儿童水痘IgG抗体的几何均值呈现偏态分布,不同年龄与地区的儿童对其都有统计学的意义。最终得出结论是1—4岁的儿童应作为接种水痘疫苗的首选对象。
In order to study how protective the vaccine against childhood chickenpox could be, explore ways to boost immunity. The method used was to collect 200 finger-tip blood samples from 0 to 14-year-old children vaccinated with a small dose of varicella vaccine and determine the varicella IgG antibody using a fixed-dose enzyme-linked immunosorbent assay while observing the prevalence of varicella in children. The test results show that the geometric mean of IgG antibodies against chicken pox presents a skewed distribution, and children of different ages and regions have statistical significance. The final conclusion is that children 1-4 years of age should be vaccinated as the preferred target of chickenpox vaccination.