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目的观察重度慢性阻塞性肺疾病(COPD)合并营养不良患者发生率,评价早期肠内营养治疗的疗效。方法 112例重度COPD患者随机分为肠内营养组(EN组)、肠外营养组(PN组),均在营养支持前及营养支持1周后观察体重指数(IBM)、血清白蛋白、血红蛋白、总淋巴细胞计数、SGRQ评分。结果治疗后两组血清白蛋白、血红蛋白、淋巴细胞总数、SGRQ评分与治疗前相比有明显改善(P<0.05);治疗后两组体重指数较治疗前无明显改善(P>0.05),两组治疗前后SGRQ评分有显著差异(P<0.05)。结论 PN及PN均能改善重度COPD患者的营养状态,PN在临床疗效上优于PN。
Objective To observe the incidence of patients with severe chronic obstructive pulmonary disease (COPD) complicated with malnutrition and to evaluate the efficacy of early enteral nutrition therapy. Methods One hundred and twelve patients with severe COPD were randomly divided into enteral nutrition group (EN group) and parenteral nutrition group (PN group). Body weight index (IBM), serum albumin, hemoglobin , Total lymphocyte count, SGRQ score. Results After treatment, serum albumin, hemoglobin, total lymphocyte count and SGRQ score were significantly improved in both groups (P <0.05). After treatment, the body mass index of both groups had no significant improvement (P> 0.05) There was significant difference in SGRQ scores before and after treatment (P <0.05). Conclusion PN and PN can improve the nutritional status of patients with severe COPD, PN is superior to PN in clinical efficacy.