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胰高血糖素样肽1（GLP-1）是目前用于治疗2型糖尿病的新型药物，因其以葡萄糖依赖方式刺激胰岛素释放而得到广泛应用。脂肪因子是由脂肪细胞分泌的活性因子，可以参与体内多种代谢功能的调节，并在许多疾病的发生、发展中发挥关键作用。因此，深入研究GLP-1对脂肪因子的调节作用，将为更好地应用GLP-1治疗代谢性疾病提供依据。“,”Glucagon-like peptide-1(GLP-1) is widely used in the treatment of type 2 diabetes mellitus because of stimulating glucose-dependent insulin secretion in pancreatic βcells.Adipocytokines are secreted by adipocytes,involved in multiple metabolic functions in vivo and play a key role in the development of many diseases.The research on the regulation of GLP-1 to adipokines,will provide a new way to the treatment of metabolism diseases.