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收集了安徽省某地区地甲病流行患者的血、尿、发样，病区的饮水样、谷物、蔬菜样和环境地质样共计６９９个，同时收集了该地非病区水样和环境地质样２８２个。水样直接进样，其它样品经湿法分解后，用离子色谱法测定其中的碘和溴的含量。统计分析表明，病区地甲病患病率与饮水中碘的含量密切相关，也与环境地质如地貌、地质构造及水文地球化学等条件密切相关。碘含量低的石灰岩地区，地甲病患病率高。
A total of 699 blood, urine and hair samples were collected from drinking water samples, cereals, vegetables samples and environmental geological samples in endemic areas in Anhui Province. Meanwhile, the water samples collected from non-endemic areas and environmental geology 282 Water samples were injected directly, other samples by wet decomposition, the determination of iodine and bromine by ion chromatography. Statistical analysis shows that prevalence of endemic toxemia in ward is closely related to iodine content in drinking water and is also closely related to environmental geology such as landform, geological structure and hydrogeochemistry. Limestone areas with low iodine content have a high prevalence of tophi.