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Purpose: To observe the immunological changes in epiretinal membranes from the patients with proliferative vitreoretinopathy (PVR).Methods: Twelve samples of epiretinal membranes obtained during vitreous surgeries for PVR were examined by direct and indirect immunofluorescein histochem-istry.Results: The cellular membranes in 8 cases were composed of retinal pigment epithelial cells, fibroblast-like cells, macrophages and collagen. Positive stainings of IgG. C3, collagen type 1 and macrophage-marker Ki-M7(CD68) was seen in the membranes.Conclusion : The results indicate that humoral immune components and macrophages may play an important role in the development of epiretinal membrane formation. Eye Science 1996; 12:10-14.
Purpose: To observe the immunological changes in epiretinal membranes from the patients with proliferative vitreoretinopathy (PVR). Methods: Twelve samples of epiretinal membranes obtained during vitreous surgeries for PVR were examined by direct and indirect immunofluorescein histochem-istry. Results: The cellular membranes in Positive staining of IgG. C3, collagen type 1 and macrophage-marker Ki-M7 (CD68) was seen in the membranes. Confluence: The results of the findings that humoral immune components and macrophages may play an important role in the development of epiretinal membrane formation. Eye Science 1996; 12: 10-14.