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中间型地中海贫血(以下“地中海贫血”简称“地贫”)包括一组不同基因型的综合征,但有相似中等程度的临床及血液学表现。本文报告12例中间型地贫携带者,其结果为: 临床资料:2例小于15岁,5例15～20岁,5例大于20岁。全部体检正常,无骨骼改变。8例在手术及怀孕时曾输血。4例已有子女。7例曾作脾切除术,另5例脾大3～6指,全部有肝大及轻度黄疸。2例胆红素曾高达5.4mg％,3例有胆石,1例踝部有营养性溃疡。全部病例的症状均不会因其它疾病而加重。血液学资料:Hb8.76±1.35克％,纯合子型Hb平均值常较低,RBC数,PCV,
Intermediate thalassemia (hereinafter referred to as “thalassemia” for thalassemia) includes a group of syndromes of different genotypes but with similar intermediate-level clinical and hematologic manifestations. This article reports 12 cases of intermediate-type carriers of thalassemia, the results are as follows: Clinical data: 2 cases less than 15 years old, 5 cases 15 to 20 years old, 5 cases more than 20 years old. All physical examination normal, no skeletal changes. Eight patients had blood transfusions during surgery and pregnancy. 4 cases have children. 7 cases had splenectomy, and the other 5 cases splenomegaly 3 ~ 6 fingers, all with hepatomegaly and mild jaundice. 2 cases of bilirubin had as high as 5.4mg%, 3 cases of gallstones, 1 case of nutritional ulcer at the ankle. All cases of symptoms will not be aggravated by other diseases. Hematology data: Hb8.76 ± 1.35 g%, homozygous Hb mean low, RBC count, PCV,