本报告是美国达拉斯等18个城市医院组成的新生儿脑膜炎协作研究组提出的。观察对象包括细菌学证实的≤2岁的固紫阴性杆菌脑膜炎患儿117例,主耍由大肠杆菌引起(82例),其次为肠炎杆菌(7例》。随机分成2组:(甲)胃肠道外给药组65例:氨节青雄素50毫克/公斤每12小时一次静注((7天的婴儿》,或70毫克/公斤每8小时一 This report was made by a collaboration team of neonatal meningitis consisting of 18 urban hospitals in the United States such as Dallas. The subjects included 117 bacilli clinically confirmed children with solid-negative bacillus meningitis (≤2 years), mainly caused by Escherichia coli (82 cases), followed by Enterocolitis (7 cases). They were randomly divided into two groups: Sixty-five patients in the parenteral administration group were treated with amoxicillin 50 mg / kg once every 12 hours (7-day infants, or 70 mg / kg every 8 hours