唐氏综合征(DS)又称21-三体综合征或先天愚型,是人类最常见的染色体异常畸变综合征。它是由于各种因素影响导致母亲生殖细胞在成数分裂时不分离,第21号染色体由二体变异成三体所致。国内外报道其发病率在1/600~1/800[1]。 Down Syndrome (DS), also known as 21-trisomy syndrome or Down’s syndrome, is the most common human chromosome aberration syndrome. It is due to a variety of factors leading to the mother’s germ cells in the division does not separate, chromosome 21 from two body variation due to three bodies. Domestic and foreign reports its incidence in the 1/600 ~ 1/800 [1].