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目的 探讨胃癌术中胃腔和腹腔内温热灌洗化疗对胃癌术后腹膜转移和生存期的影响。方法 将胃癌患者随机分为A、B 2组 ,各 30例。A组单纯手术 ,B组手术加胃腔和腹腔内温热灌洗化疗。观察其并发症及 1、3年生存率。结果 A组 1年生存率为 80 .5 % ,B组为 80 .0 % ,P >0 .0 5。A组 3年生存率为 40 .5 % ,B组为 5 0 .5 % ,有非常显著性差异 ,P <0 .0 1。A、B 2组并发症无显著性差异。结论 胃癌手术辅以胃腔及腹腔内温热灌洗化疗 ,对于防治癌肿腹膜转移 ,提高生存率有重要意义。
Objective To investigate the effect of intragastric and intraperitoneal warm lavage chemotherapy on the peritoneal metastasis and survival of gastric cancer patients after operation. Methods Patients with gastric cancer were randomly divided into A, B 2 group, each 30 cases. A group of simple surgery, B group operation plus stomach and intraperitoneal warm lavage chemotherapy. Observe the complications and 1, 3 year survival rate. Results The 1-year survival rate was 80.5% in group A, 80.0% in group B, P> 0.05. The 3-year survival rate was 40.5% in group A and 50.5% in group B, with significant difference (P <0.01). A, B 2 group no significant difference in complications. Conclusion Gastric cancer surgery combined with intragastric and intraperitoneal warm lavage chemotherapy is of great significance for the prevention and treatment of cancer peritoneal metastasis and survival rate.