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一、历史背景多年来关于剥脱综合征(Exfoliation Syndrome)有许多描述和命名,Vogt(1925)首次提出老年性晶体囊膜剥脱和晶体囊膜性青光眼(Senile exfoliation of the lens capsule and glaucoma capsular),以后又有老年性炎性青光眼(Glaucoma senilis),晶体囊膜假性剥脱(Pseudoexfoliation of the lens capsule)等名称。电子显微镜研究证实除晶体囊膜外,眼的其他结构如房角小梁、睫状体、虹膜、结膜等都存在着剥脱物质。晶体摘出后,剥脱物质仍存在于玻璃体前表面,说明晶体囊膜并不是剥脱物质的唯一来源。鉴于眼的多种结构被累及,所以Sunde(1956)称之为剥脱综合征,这个名称是迄今为止最能为大家所接受的。Eagle等(1979)发现睫状体后短动脉被累及,提示剥脱综合征是一种基底膜疾病,因而命名为基底膜剥脱综合征(Basement Membrane Exfoliation Syndrome)。
I. Background There are many descriptions and nomenclatures for Exfoliation Syndrome over the years. Vogt (1925) first proposed Senile exfoliation of the lens capsule and glaucoma capsular, Glaucoma senilis and Pseudoexfoliation of the lens capsule are names for later. Electron microscopy studies have shown that in addition to the crystalline capsule, other structures of the eye such as trabecular, ciliary body, iris, conjunctiva, etc. exist stripping substances. After exfoliation, stripping material is still present on the anterior surface of the vitreous, indicating that the crystalline capsule is not the only source of stripping material. Given the variety of ocular structures involved, Sunde (1956) called it the exfoliation syndrome and is by far the most accepted. Eagle et al. (1979) found that the posterior ciliary body is involved in the short aorta, suggesting that stripping syndrome is a basement membrane disease and hence the name Basement Membrane Exfoliation Syndrome.