例1,男性,21岁.因反复咳喘、低热3年于1993年11月2日就诊.患者自1991年以来每年8～9月间反复出现咳嗽,少量白沫痰、胸闷、气急伴乏力、低热,经青霉素等抗炎治疗无效,曾诊断为肺结核,给予异烟肼、利福平、链霉素等正规联合化疗9个月无好转.每年发作延续2个月.无哮喘既往史和家族史.体查无明显阳性体征.血白细胞7.8×10~9/L,中性粒细胞60%,嗜酸细胞3%,IgG 21.0/L,IgA 0.9/L,IgM 1.4/L,lgE(—).X线胸片提示两肺纹理增多,两肺野弥漫性斑点状阴影,以中下野为著.肺功能检查提示中度限制性通气障碍.追问病史,患者居住之乡村种植大量薄荷.患者每年8～9月间从事收割和初加工薄荷的劳动.时值秋季,潮湿的薄荷堆放一段时日即发霉.因患者与堆放的薄荷接触频繁,怀疑发病与霉薄荷有关.令患者进入堆放枯薄荷的屋内20分钟即离开.4小时后患者感胸 Example 1, male, 21 years old due to repeated cough, fever for 3 years in November 2, 1993. Patients since 1991 each year from August to September recurrent cough, a small amount of white sputum, chest tightness, shortness of breath with acute urgency , Fever, penicillin and other anti-inflammatory treatment ineffective, has been diagnosed as tuberculosis, given isoniazid, rifampicin, streptomycin and other regular combination chemotherapy 9 months without improvement .Every year for 2 months without a prior history of asthma Family history, physical examination no obvious positive signs of leukocyte 7.8 × 10 ~ 9 / L, 60% of neutrophils, 3% of eosinophils, IgG 21.0 / L, IgA 0.9 / L, IgM 1.4 / L, -). X-ray showed two lungs increased texture, the two lung fields diffuse speckled shadows, with the middle and lower back as the lung function tests prompted moderate restrictive ventilation disorders. History, the patient living in the village planted a large number of mint. The patient engages in the process of harvesting and initial processing of mint annually between August and September of the year.Machine is moldy in autumn when it is stored for a period of time.Due to the frequent contact of the patient with mint, The mint’s house leaves within 20 minutes and the patient feels chest four hours later