论文部分内容阅读
近年来,应用维生素K(VK)治疗胆绞痛、胃肠道平滑肌痉挛性腹痛、支气管哮喘、痛经等均收到满意效果。最近,笔者及傅氏等又分别报道了VK治疗肾输尿管绞痛有同样疗效。为了解VK对输尿管蠕动功能的影响,探讨VK缓解输尿管绞痛的作用机理,我们作了动物实验研究。现将初步结果报告如下。实验方法一、在体实验健康成年犬14只,体重12～18k8,雌雄不拘,戊巴比妥钠静脉注射麻药(30mg/kg)。手术开腹,摘除一侧输尿管用以离体实验。用一根聚氯乙烯导管插入肾盂并结扎固定,以保持该侧肾脏尿液的通畅。在另一侧输
In recent years, the use of vitamin K (VK) in the treatment of biliary colic, gastrointestinal smooth muscle spasm abdominal pain, bronchial asthma, dysmenorrhea have received satisfactory results. Recently, the author and Fu et al. separately reported that VK has the same curative effect in the treatment of renal ureteralgia. In order to understand the effect of VK on ureteral peristaltic function and to explore the mechanism of VK in relieving ureteralgia, we conducted animal experiments. The preliminary results are reported below. Experimental methods 1. In vivo experiments Healthy adult dogs, 14 weighing 12 to 18k8, male or female, pentobarbital sodium intravenous injection of anesthetic (30mg/kg). Surgical laparotomy, removal of one side of the ureter for ex vivo experiments. A polyvinyl chloride catheter was inserted into the renal pelvis and ligated to maintain patency of the urine of the side of the kidney. Lose on the other side