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抑癌基因ｐ１６在多种肿瘤中有缺失或突变〔１〕。本文应用免疫组化方法观察５６例肾细胞癌（ＲＣＣ）中ｐ１６蛋白的表达，结合观察增殖细胞核抗原（ＰＣＮＡ）的表达状况，分析ｐ１６蛋白表达与ＲＣＣ细胞增殖活性及预后的关系。１材料和方法５６例ＲＣＣ中，男性４０例...
Tumor suppressor gene p16 in a variety of tumors have a deletion or mutation 〔1〕. In this paper, the expression of p16 protein in 56 cases of renal cell carcinoma (RCC) was observed by immunohistochemistry, and the relationship between the expression of p16 protein and the proliferation and prognosis of RCC cells was analyzed by observing the expression of proliferating cell nuclear antigen (PCNA). 1 Materials and Methods 56 cases of RCC, 40 males ...