阑尾原发性淋巴瘤,仅占胃肠道淋巴瘤的0.015%,极其罕见。其临床表现与急性阑尾炎相似,表现为右下腹隐痛,血白细胞正常或升高。术前腹部B超及CT等影像检查明确诊断困难,需术后病理检查方可确诊。由于临床表现缺乏特异性,容易漏诊、误诊。本文报道1例我院2015年3月收治的原发性阑尾弥漫性大B细胞淋巴瘤,探讨其临床表现、病理学诊断要点及免疫组化特征。 Appendiceal primary lymphoma, only 0.015% of gastrointestinal lymphoma, is extremely rare. Its clinical manifestations and acute appendicitis similar to the performance of the right lower quadrant pain, white blood cells normal or elevated. Preoperative abdominal ultrasound and CT and other imaging confirmed a clear diagnosis difficult to be confirmed by postoperative pathological examination. Due to the lack of specificity of clinical manifestations, easy to missed diagnosis, misdiagnosis. This article reports a case of our hospital in March 2015 admitted primary diffuse large B-cell lymphoma, to explore its clinical manifestations, pathological diagnosis points and immunohistochemical characteristics.