论文部分内容阅读
目的 :探讨选择性动脉内化疗在中、晚期鼻咽癌综合治疗中的应用价值。方法 :选择70例局部中、晚期鼻咽癌初治患者 ,随机分成二组(各35例) ,分别进行选择性动脉化疗(IACT)加放疗和全身化疗(SCT)加放疗 ,并采用配对的方法选择同期单纯放疗(RT)的鼻咽癌患者作为对照组 ,于放疗后对三组的疗效进行比较。结果 :IACT组完全缓解率及2年局控率为65.7%及82.9% ,SCT组为54.3%及77.1% ,RT组为42.9 %及51.4 %。结论 :选择性动脉内化疗加放疗治疗中、晚期鼻咽癌 ,短期疗效显著 ,副作用轻
Objective: To explore the value of selective arterial chemotherapy in the comprehensive treatment of advanced nasopharyngeal carcinoma. Methods: A total of 70 patients with locally advanced nasopharyngeal carcinoma of the nasopharyngeal carcinoma were randomly divided into two groups (n = 35 each). The patients underwent selective intraarterial chemotherapy (IACT) combined with radiotherapy and systemic chemotherapy (SCT) plus radiotherapy. Methods Nasopharyngeal carcinoma patients treated with radiotherapy alone (RT) were selected as the control group, and the efficacy of the three groups was compared after radiotherapy. Results: The complete response rate and two-year local control rate in IACT group were 65.7% and 82.9%, 54.3% and 77.1% in SCT group and 42.9% and 51.4% in RT group. Conclusion: Selective intra-arterial chemoradiation combined with radiotherapy for the treatment of advanced nasopharyngeal carcinoma has significant short-term curative effect and mild side effects