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通过西安地区30年间肾综合征出血热802例的死因回顾性研究,看出其主要死因百分比的变迁。死于休克者从1950与1960年代的51.9%渐降至1980年代的27.8%,其中1970年代较1950与1960年代相差显著(P<0.05);至1970年代并发急性肾衰病死百分比升至第一位(57.2%);1980年代以来除急性肾衰仍为主要死因(47.8%)外,死于继发感染明显增多(P<0.01)。为降低危重型出血热病死率,除抗休克、抗肾衰等治疗外,还应特别重视继发感染的防治措施。
A retrospective study of the cause of death of 802 cases of hemorrhagic fever with renal syndrome over 30 years in Xi’an showed that the percentage of major causes of death was changed. The number of those who died of shock dropped from 51.9% in 1950 and 1960s to 27.8% in 1980s, of which the difference between 1970s and 1950s was significant (P <0.05); the percentage of deaths from acute renal failure rose to first in the 1970s (57.2%). Since the 1980s, except acute renal failure (47.8%), the number of deaths from secondary infection was significantly increased (P <0.01). To reduce the critical hemorrhagic fever mortality, in addition to anti-shock, anti-renal failure and other treatment, special attention should also be given to the prevention and treatment of secondary infection.