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AIM:To investigate the therapeutic value of livertransplantation for advanced hepatocellular carcinoma(HCC).METHODS:Twenty-eight patients with advanced HCC weretreated by liver transplantation from August 2000 to October2003 at Peking University Third hospital.All the patientswere followed up to evaluate the result.RESULTS:The longest follow-up duration was 3 years and3 mo.Till the end of the follow-up period,17 patients hadalready died and 11 were alive.Of those who died,10 patientsdied of tumor recurrence,4 died during the perioperativeperiod,2 died of variceal bleeding,and 1 died of biliarycomplication.According to life table method,the 1-,2-,and3-year survival rates were 87.5%,52.5%,and 42.9%,respectively.CONCLUSION:Liver transplantation provides a newtreatment under the circumstance of lacking of an effectivetreatment for advanced HCC at present.Some patients cansurvive for a relatively long time free of tumor.In our country,if the patients can afford liver transplantation,advanced HCCwithout extrahepatic metastasis is an indication for livertransplantation at present.
AIM: To investigate the therapeutic value of livertransplantation for advanced hepatocellular carcinoma (HCC). METHODS: Twenty-eight patients with advanced HCC weretreated by liver transplantation from August 2000 to October2003 at Peking University Third hospital. All the patientswere followed up to evaluate the result .RESULTS: The longest follow-up duration was 3 years and 3 mo. Till the end of the follow-up period, 17 patients hadalready died and 11 were alive.Of those who died, 10 patientsdied of tumor recurrence, 4 died during the perioperative period , 2 died of variceal bleeding, and 1 died of biliary complication. Accredited to life table method, the 1-, 2-, and 3- year survival rates were 87.5%, 52.5%, and 42.9%, respectively.CONCLUSION: Liver trafficking provides a newtreatment under the circumstance of lacking of an effective treatment for advanced HCC at present. Home patients cansurvive for a relatively long time free of tumor. in our country, if the patients can afford liver transplantation, advance d HCCwithout extrahepatic metastasis is an indication for livertransplantation at present.