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本文作者选用2岁以下的雌性杂种家兔,隔离20天后,应用求偶素,四氧嘧啶及20—甲基坦蒽诱发子宫内膜腺癌。观察了这些药物和子宫内膜腺癌的关系,并从形态学方面探讨了子宫内膜腺癌的发展过程。实验共分四组: 甲组只给雌激素(11例):每周注射求偶二醇5毫克,连续15周。以后每两个月取子宫内膜活检一次,停药后10个月时将兔处死,并作组织学检查。
The authors selected female hybrid rabbits under 2 years of age, isolation of 20 days, the application of allium, alloxan and 20-methyl-anthracene-induced endometrial adenocarcinoma. The relationship between these drugs and endometrial adenocarcinoma was observed, and the development of endometrial adenocarcinoma was discussed morphologically. The experiment was divided into four groups: Group A only given estrogen (11 cases): 5 mg weekly injection of diol for 15 consecutive weeks. After every two months to take the endometrial biopsy once, 10 months after stopping the rabbit was executed, and for histological examination.