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目的从血清学和发病率评价天津市<20岁人群乙型病毒性肝炎(乙肝)控制效果。方法乙肝血清学和报告发病率资料分别来源于天津市疾病预防控制中心1992年、2009年抽样调查结果和传染病疫情汇编。结果 2009年抽样调查了<20岁人群1207人,抗乙肝病毒表面抗原抗体[Antibody to Hepatitis B Virus(HBV)Surface Antigen(HBsAg),Anti-HBs]阳性率为66.03%,其中1～4岁人群阳性率最高(81.66%),年龄组间差异有统计学意义(χ2=53.23,P<0.05);HBsAg和抗乙肝病毒核心抗原抗体(Antibody to HBV Core Antigen,Anti-HBc)阳性率分别为0.91%和2.24%,Anti-HBc阳性率年龄组间的差异有统计学意义(χ2=10.05,P<0.05)。1991～1993年<20岁人群乙肝年平均报告发病率为14.14/10万(标化,下同),2007～2009年为9.46/10万,下降了33.00%。≥20岁人群在上述相同时间段内的乙肝报告发病率分别为39.13/10万和44.57/10万,上升了13.90%。结论从乙肝血清学指标和发病率均证实:天津市控制<20岁人群乙肝的效果明显。
Objective To evaluate the control effect of hepatitis B (hepatitis B) in Tianjin population <20 years old from serology and morbidity. Methods Hepatitis B serology and reported incidence data were from the Tianjin Center for Disease Control and Prevention in 1992, 2009 sampling survey results and compilation of infectious disease outbreaks. Results A total of 1,207 people aged <20 years were surveyed in 2009, and the positive rate of anti-HBeAg (HBsAg) and Anti-HBs was 66.03% (Χ2 = 53.23, P <0.05). The positive rates of HBsAg and anti-HBV Core Antigen (Anti-HBc) were 0.91 % And 2.24% respectively. There was a significant difference between the age groups of anti-HBc positive rate (χ2 = 10.05, P <0.05). From 1991 to 1993, the average annual incidence of hepatitis B in the population of 20 years old was 14.14 / 100000 (standardized, the same below). From 2007 to 2009, it was 9.46 / 100000, a decrease of 33.00%. The prevalence of hepatitis B in people aged ≥20 years was 39.13 / 100,000 and 44.57 / 100,000, respectively, an increase of 13.90% over the same period of time. Conclusion Hepatitis B serology and morbidity confirmed that the effect of controlling hepatitis B in Tianjin is obvious.