论文部分内容阅读
Dubin和Johnson二氏于1954年首次描述了本综合征,其典型临床病理特点为高结合胆红素血症、磺溴酞钠试验异常潴留,口服胆囊造影不显影以及肝细胞内有棕褐色颗粒沉着。其后,文献上陆续发表了一些变异型病例报告。Burka等(Am J Med Sci,242(6):746,1961)报道一例无黄疸型本综合征患者;Sagild等(Anm Iut Med,56(2):308,1962)则发现一例同时兼具Gilbert型与Dubin-Johnson型肝细胞功能缺陷的患者。本文报告一例病理上符合Dubin-Johnson综合征,但血清胆红素却以非结合性增高为主。病例报告孙×,男,24岁。1974年5月27日入院。患者早在
Dubin and Johnson first described the syndrome in 1954, with typical clinical and pathological features of hyperbilirubinemia, abnormal retention of sodium sulfochromate, absence of oral cholecystography, and the presence of tan particles in hepatocytes calm. Since then, the literature published some cases of variant cases. A case of jaundice-free syndrome was reported by Burka et al. (Am J Med Sci, 242 (6): 746, 1961); Sagild et al. (Anm Iut Med, 56 And Dubin-Johnson-type hepatocytes in patients with functional defects. This article reports a case of pathological compliance with Dubin-Johnson syndrome, but the serum bilirubin mainly non-binding increased. Case report Sun ×, male, 24 years old. May 27, 1974 admitted to hospital. The patient is early