结核病药物抗性威胁着控制该病所作的努力。本文报告１９９４～１９９７年３５个国家参加世界卫生组织国际协会全球调查４种药物对结核病抗性发展趋势。方法　资料来自横断面研究报告。参与国遵照标准规程，保证使用代表性标本，准确治疗病历，标准实验室方法以及常规要求等。 Drug resistance to tuberculosis threatens the efforts to control the disease. This article reports on the trend of TB resistance in 35 countries participating in the World Health Organization International Association’s global survey of four drugs from 1994 to 1997. Methodology data from the cross-sectional study. Participating countries follow standard protocols, guaranteeing the use of representative specimens, accurate treatment of medical records, standard laboratory methods, and general requirements.