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抑制肾素-血管紧张素-醛固酮系统(RAAS)药物在心血管疾病的预防和治疗中发挥重要作用。联合应用血管紧张素转化酶抑制药(ACEI)和血管紧张素Ⅱ受体拮抗药(ARB)主要用于蛋白尿、RAAS抑制不完全的心力衰竭。联合应用醛固酮抑制剂和ACEI或ARB可降低心力衰竭患者的死亡率。尚需对联合应用肾素抑制药和其他RAAS抑制药做进一步研究。
Inhibition of renin-angiotensin-aldosterone system (RAAS) drugs plays an important role in the prevention and treatment of cardiovascular diseases. Combination of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin II receptor antagonist (ARB) is mainly used for proteinuria, RAAS incomplete heart failure. Combined use of aldosterone inhibitors and ACEI or ARB can reduce mortality in patients with heart failure. Still need to be combined with renin inhibitors and other RAAS inhibitors do further research.