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再生障碍性贫血(再障)和纯红细胞再生障碍性贫血(纯红再障)的病因及发病机制仍未完全清楚,目前认为系与机体的免疫功能紊乱有密切关系。我们最近采用OKT系列单克隆抗体检测再障和纯红再障患儿外周血T细胞亚群,对其发病机制作一初步探讨。材料与方法一、病例:共检测再障和纯红再障10例(按1986年杭州儿科血液病会议制订的标准进行诊断),其中慢性再障7例,男6例,女1例;纯红再障3例,均为男性。以上病例均在治疗前或2月内未用皮质激素
Aplastic anemia (aplastic anemia) and pure red cell aplasia (pure red aplastic anemia) etiology and pathogenesis is still not fully understood, now that the system with the body’s immune dysfunction are closely related. We recently used OKT monoclonal antibodies to detect peripheral blood T cell subsets in children with aplastic anemia and pure azoospermia and made a preliminary study on their pathogenesis. Materials and Methods First, the case: A total of 10 cases of aplastic anemia and pure aplastic anemia (according to the Hangzhou pediatric blood disease meeting in 1986 to develop the diagnostic criteria), including 7 cases of chronic aplastic anemia, 6 males and 1 female; pure Red aplasia in 3 cases, both men. The above cases were not treated with corticosteroids before or within 2 months