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观察了１０例。α－干扰素治疗慢性粒细胞白血病时，内生ＬＡＫ细胞活性与细胞遗传学缓解的关系。其结果为干扰素治疗前慢性粒细胞白血病（ＣＭＬ）患者无内生ＬＡＫ细胞活性。于干扰素治疗后逐渐出现内生ＬＡＫ细胞活性，在６例检测出ＬＡＫ细胞活性的病例中均出现不同程度的ｐｈ阳性细胞比例下降，从而推测，α－干扰素治疗ＣＭＬ时部分病人细胞遗传学缓解可能与α－干扰素诱生体内ＬＡＫ细胞增多参与肿瘤免疫应答反应有关。
Ten cases were observed. Relationship between endogenous LAK cell activity and cytogenetic response in the treatment of chronic myeloid leukemia with interferon alpha. The result is no intrinsic LAK cell activity in patients with pre-interferon treatment of chronic myeloid leukemia (CML). Endogenous LAK activity gradually emerged after interferon treatment, and the percentage of ph positive cells decreased in all 6 cases detected LAK cell activity, suggesting that some patients cytogenetics Relief may be associated with IFN-α-induced LAK cells increased tumor immune response involved.