糖尿病脑病是糖尿病慢性并发症之一,长期高血糖状态下可引起中枢神经系统的损害,从而导致认知功能的下降。Deigaard通过脑代谢、神经生化、脑电生理、脑形态学及行为学等方面的研究,提出了糖尿病性脑病的概念。糖尿病脑病以获得性认知障碍和行为缺陷为特征,以轻、中度认知功能障碍为主,临床主要表现为学习能力下降,记忆功能减退,空间时间定向困难,语言、理解判断和复杂信息处理能力下降,重者甚至可发展为痴呆。1型糖尿病认知功能损害主要在联 Diabetic encephalopathy is one of the chronic complications of diabetes, chronic high blood sugar can cause damage to the central nervous system, resulting in decreased cognitive function. Deigaard put forward the concept of diabetic encephalopathy through brain metabolism, neurobiochemistry, brain electrophysiology, brain morphology and behavioral studies. Diabetic encephalopathy is characterized by acquired cognitive impairment and behavioral deficits, with mild to moderate cognitive impairment. The main clinical manifestations are decreased learning ability, memory loss, difficulty in time and space orientation, language, comprehension judgment and complex information Decreased processing power, severe cases can even develop into dementia. Type 1 diabetes cognitive impairment mainly in the United