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目的 评价左氧氟沙星治疗肺部感染性疾病的临床疗效、不良反应和安全性。方法 5 2例肺部感染患者(男 38例 ,女 14例 ) ,口服左氧氟沙星片剂 ,每次 0 .2 g,每日两次 ,疗程 7～ 10 d;逐日观察症状、体征的变化及不良反应 ;本组全部病例治疗前后做痰培养和药敏试验 ,并检查肝肾功能。结果 5 2例患者经过治疗 ,痊愈 5 7.7%、显效 2 8.8% ,总有效率 (痊愈 +显效 ) 86 .5 % ,痰菌清除率为 75 .6 % ,不良反应发生率为 9.6 %。结论 左氧氟沙星片剂临床疗效可靠 ,安全性好 ,适合于各种轻、中、重度肺部感染性疾病的治疗
Objective To evaluate the clinical efficacy, adverse reactions and safety of levofloxacin in the treatment of pulmonary infectious diseases. Methods Fifty-two patients with pulmonary infection (38 males and 14 females) were given oral levofloxacin tablets at 0.2 g twice daily for 7-10 days. The symptoms and signs were observed daily Reaction; all patients in this group before and after treatment to do sputum culture and susceptibility testing, and check the liver and kidney function. Results Fifty-two patients were cured, with a cure rate of 5 7.7% and a cure rate of 8.8%. The total effective rate (cure + effective) was 86.5%. The sputum clearance rate was 75.6% and the adverse reaction rate was 9.6%. Conclusion Levofloxacin tablets have reliable clinical efficacy and good safety, and are suitable for the treatment of various mild, moderate and severe pulmonary infectious diseases