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目的:观察小梁切除术联合同种异体羊膜植入术治疗难治性青光眼的疗效。方法:对40例(54只眼)难治性青光眼行小梁切除术联合羊膜移植手术,术后随访6～12个月。观察术后滤过泡形态和功能,眼压,视力变化,并发症等情况。结果:54只眼术后全部形成并保持功能性滤过泡,眼压除2只眼需局部应用降眼压药控制在21 mmHg以下外,其余眼压均在10 mmHg～21 mmHg之间。未发现因羊膜植入所致的并发症。结论:羊膜移植在难治性青光眼滤过性手术中的应用疗效显著,且无毒副作用,可推广应用。
Objective: To observe the effect of trabeculectomy combined with allogeneic amniotic membrane implantation in the treatment of refractory glaucoma. Methods: Forty cases (54 eyes) refractory glaucoma underwent trabeculectomy combined with amniotic membrane transplantation. The patients were followed up for 6 to 12 months. Postoperative filtration bleb morphology and function, intraocular pressure, visual acuity changes, complications and so on. Results: Fifty-four eyes formed and maintained functional filtration bleb. Intraocular pressure (IOP) was controlled within 21 mmHg by topical application of IOP-lowering ophthalmic solution. The intraocular pressure was between 10 mmHg and 21 mmHg. No complications due to amniotic membrane implantation were found. Conclusion: The amniotic membrane transplantation in the treatment of refractory glaucoma surgery has significant curative effect, and no toxic and side effects, can be popularized and applied.